Prune Belly Syndrome (PBS) is a rare congenital syndrome characterized by three main features: abdominal wall flaccidity, bilateral intra-abdominal cryptorchidism and urological abnormalities. In this study we describe the case of a 2,600 gr baby, born at the Central Hospital of Beira, in Mozambique. Our study confirms that in a low-income country only conservative management can be delivered, and therefore prognosis is worse and less effective than high-income countries.